MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells.

نویسندگان

  • Stefan Wuttke
  • Simone Braig
  • Tobias Preiß
  • Andreas Zimpel
  • Johannes Sicklinger
  • Claudia Bellomo
  • Joachim O Rädler
  • Angelika M Vollmar
  • Thomas Bein
چکیده

We report the synthesis of MOF@lipid nanoparticles as a versatile and powerful novel class of nanocarriers based on metal-organic frameworks (MOFs). We show that the MOF@lipid system can effectively store dye molecules inside the porous scaffold of the MOF while the lipid bilayer prevents their premature release. Efficient uptake of the MOF@lipid nanoparticles by cancer cells makes these nanocarriers promising for drug delivery and diagnostic purposes.

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عنوان ژورنال:
  • Chemical communications

دوره 51 87  شماره 

صفحات  -

تاریخ انتشار 2015